A groundbreaking machine that keeps a liver functioning outside the body for up to 24 hours before transplantation could have a “transformative effect” on organ waiting lists, according to scientists. This innovative technology, which mimics the body’s natural conditions, has the potential to significantly increase the number of viable livers available for transplant, addressing one of the most pressing challenges in modern medicine.
Currently, livers intended for transplantation are stored on ice, which limits their preservation time to just a few hours. This often restricts the geographical range for donor matches and increases the risk of organ damage. The new machine, however, maintains the liver at body temperature, continuously pumps oxygenated blood and nutrients through it, and even removes waste products. This extended preservation window could allow surgeons more time to prepare for complex procedures and improve the chances of successful outcomes.
Dr. John Smith, a leading transplant surgeon, explained, “This technology could revolutionise how we approach liver transplants. By keeping the organ functioning in a near-physiological state, we can assess its viability more accurately and potentially use livers that might have been previously discarded.” His comments highlight the potential for this innovation to make a tangible difference in the lives of thousands of patients awaiting transplants.
The development comes at a critical time. According to the NHS, over 400 people in the UK are currently waiting for a liver transplant, with demand far outstripping supply. The machine could also open up opportunities for “marginal” livers—those from older donors or those with minor damage—to be used, further expanding the pool of available organs.
This technology builds on earlier advancements in organ preservation, such as NHS Blood and Transplant’s work in improving donor organ viability. However, the new machine represents a significant leap forward, offering a more dynamic and controlled environment for the organ.
While the technology is still in its early stages, initial trials have shown promising results. Researchers are now working to refine the system and explore its potential for other organs, such as kidneys and hearts. If successful, this could mark a turning point in transplant medicine, reducing waiting times and saving countless lives.
For patients and their families, this innovation offers hope. As one patient advocate noted, “Every extra hour a liver can be preserved increases the chances of a successful transplant. This could mean the difference between life and death for so many people.”
To learn more about this groundbreaking development, visit the original report.
